Pediatric Cardiac Arrest

Cardiopulmonary Resuscitation (CPR) guidelines recommend target values for selected CPR parameters related to rate and depth of chest compressions and ventilations, and avoidance of CPR-free intervals. However, pediatric resuscitation guidelines have largely been developed by expert clinical consensus, using data extrapolated from adult, animal, manikin, mechanical modeling, and pediatric radiological studies. There is a paucity of data collected from actual children in cardiac arrest, highlighting a major gap in the pediatric resuscitation knowledge base. In addition, there is scant data on the association of post-cardiac arrest care (PCAC) and patient outcomes after pediatric cardiac arrest.   

 

Therefore, locally and around the world, we are conducting a prospective, observational, multi-center study of pediatric cardiac arrest management. Pediatric (gestational age 37 weeks to under 18 years) cardiac arrests requiring chest compressions for at least 1 minute are eligible for enrollment.

 

This study aims to create a clinical CPR Learning Laboratory with the following objectives:

Primary: Characterize the quality of CPR and post-cardiac arrest care delivered to children across a broad spectrum of international hospitals.

Secondary:

  1. Determine the association between quantitative CPR quality measures (depth, rate, compression release, flow fraction) and survival to hospital discharge.

  2. Determine the association of survival with site-specific post-cardiac arrest care (PCAC).​

Data collection for the cardiac arrest event requires that the following information and data be entered into our pediRES-Q REDCap database:

  • Basic demographic data: Age, gender, height, weight, etc.

  • Cardiac arrest information - in-hospital or out-of-hospital: Date/time of arrest, illness category, pre-existing conditions, immediate cause of event, medications and interventions provided, duration of event, etc.

  • Quantitative CPR data from recording monitor/defibrillator (ZOLL, Philips, Physio-control).

  • Physiologic monitoring data of arterial pressures, ETCO2, ECG, etc., as available.

  • Outcomes of event, survival outcomes, along with all GCS and PCPC scores.

  • Post-arrest monitoring and laboratory data (from 2 hours prior to, to 96 hours post-ROSC, if survived).

Visit our Document Library for the most recent versions of data collection forms and aids.