Pediatric Cardiac Arrest
Cardiopulmonary Resuscitation (CPR) guidelines recommend target values for selected CPR parameters related to rate and depth of chest compressions and ventilations, and avoidance of CPR-free intervals. However, pediatric resuscitation guidelines have largely been developed by expert clinical consensus, using data extrapolated from adult, animal, manikin, mechanical modeling, and pediatric radiological studies. There is a paucity of data collected from actual children in cardiac arrest, highlighting a major gap in the pediatric resuscitation knowledge base. In addition, there is scant data on the association of post-cardiac arrest care (PCAC) and patient outcome after pediatric cardiac arrest.
This is a prospective, observational, multi-center study of pediatric cardiac arrest management. Pediatric (gestational age 37 week to <18 year) cardiac arrests requiring chest compressions for ≥1 minute are eligible for enrollment.
This study aims to create a clinical CPR Learning Laboratory with the following objectives:
Primary: Characterize the quality of CPR and post-cardiac arrest care delivered to children across a broad spectrum of international hospitals.
Determine the association between quantitative CPR quality measures (depth, rate, compression release, flow fraction) and survival to hospital discharge.
Determine the association of survival with site-specific post-cardiac arrest care (PCAC).
Data collection for the cardiac arrest event requires that the following information and data be entered into our pediRES-Q REDCap database:
Basic demographic data: Age, gender, height, weight, etc.
Cardiac arrest information - in-hospital or out-of-hospital: Date/time of arrest, illness category, pre-existing conditions, immediate cause of event, medications provided during event, defibrillation attempts, interventions provided during event, use of chest compression measuring device (monitor/defibrillator), physiologic monitoring used during event, duration of event, etc.
Quantitative CPR data from recording monitor/defibrillator (ZOLL, Philips, Physio-control)
Physiologic monitoring data of arterial pressures, ETCO2, ECG, etc., as available
Outcomes of event, survival outcomes, along with all GCS and PCPC scores.
Post-arrest hemodynamic and laboratory data (from 2 hours prior to, to 96 hours post-ROSC, if survived).
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