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These publications have been generated through the hard work, partnerships, and combined effort of the pediRES-Q Collaborative Investigators. 

Peer-reviewed Journal Publications

Most recent publications first

Ong GY, Chen ZJ, Niles DE, Srinivasan V, Sen AI, Skellett S, Ikeyama T, Del Castillo J, Berg RA, Nadkarni VM. 

J Am Heart Assoc. 2023 Jul 18;12(14):e028418. doi: 10.1161/JAHA.122.028418. Epub 2023 Jul 8. PMID: 37421276; PMCID: PMC10382104.

Background: Current pediatric cardiac arrest guidelines recommend depressing the chest by one‐third anterior–posterior diameter (APD), which is presumed to equate to absolute age‐specific chest compression depth targets (4 cm for infants and 5 cm for children). However, no clinical studies during pediatric cardiac arrest have validated this presumption. We aimed to study the concordance of measured one‐third APD with absolute age‐specific chest compression depth targets in a cohort of pediatric patients with cardiac arrest.

Lauridsen KG, Lasa JJ, Raymond TT, Yu P, Niles D, Sutton RM, Morgan RW, Fran Hazinski M, Griffis H, Hanna R, Zhang X, Berg RA, Nadkarni VM; pediRES-Q Investigators. Association of chest compression pause duration prior to E-CPR cannulation with cardiac arrest survival outcomes. Resuscitation. 2022 Aug;177:85-92. doi: 10.1016/j.resuscitation.2022.05.004. Epub 2022 May 16. PMID: 35588971.

Objective: To characterize chest compression (CC) pause duration during the last 5 minutes of pediatric cardiopulmonary resuscitation (CPR) prior to extracorporeal-CPR (E-CPR) cannulation and the association with survival outcomes.

Gray, James M. MD, MEd; Raymond, Tia T. MD; Atkins, Dianne L. MD; Tegtmeyer, Ken MD; Niles, Dana E. MS; Nadkarni, Vinay M. MD; Pandit, Sandeep V. PhD; Dewan, Maya MD, MPH;  for the pediRES-Q Investigators. Pediatric Critical Care Medicine ():10.1097/PCC.0000000000003241, April 28, 2023. | DOI: 10.1097/PCC.0000000000003241. 

In pediatric in-hospital cardiac arrest, the rate of defibrillation attempts delivered to rhythms other than ventricular fibrillation or pulseless ventricular tachycardia is not known. Previous pediatric studies have relied on bedside clinician reporting of rhythms, and the rate of inappropriate shock delivery in adults may be as high as 26%. In this cohort of international pediatric cardiac arrest patients, 30% of defibrillation attempts were delivered to nonshockable rhythms.

Ross CE, Hayes MM, Kleinman ME, Donnino MW, Sullivan AM.

Resusc Plus. 2022 Jan 14;9:100200. doi: 10.1016/j.resplu.2021.100200. PMID: 35072126; PMCID: PMC8763627.

Introduction: The clinical practice  of administering low-dose peri-arrest vasopressor boluses has been reported across a variety of hospital settings and geographic regions, but use of peri-arrest pressor boluses in pediatric ICU is rarely reported.  We aimed to describen the use of peri-arrest bolus epinephrine amongst pediatric resuscitation experts through a multinational survey.

Yu, P., Esangbedo, I., Zhang, X., Hanna, R., Niles, D., Nadkarni, V., & Raymond, T. (2023).

Cardiology in the Young, 33(1), 42-51. doi:10.1017/S1047951122000099.

Background:  Survival after paediatric in-hospital cardiac arrest is worse on nights and weekends without demonstration of disparity in CPR quality. This study aimed to determine whether CPR quality might explain the hypothesised worse outcomes of children with CHD during nights and weekends.

Lauridsen KG, Morgan RW, Dewan M, Gawronski O, Sen AI; PediRES-Q Investigators.

Resuscitation. 2021 Dec;169:39-40. doi: 10.1016/j.resuscitation.2021.10.013. Epub 2021 Oct 18. PMID: 34673154; PMCID: PMC8522673.

To the Editor, 

Adult patients with SARS-CoV-2 (COVID-19) and in-hospital cardiac arrest (IHCA) demonstrated low survival rates. Little is known about COVID-19+ IHCA in children. We present the first report describing a cohort of pediatric patients with acute COVID-19 suffering an IHCA.

Dewan M, Parsons A, Tegtmeyer K, Wenger J, Niles D, Raymond T, Cheng A, Skellett S, Roberts J, Jani P, Nadkarni V, Wolfe H.

Pediatr Qual Saf. 2021 Aug 26;6(5):e455. doi: 10.1097/pq9.0000000000000455. PMID: 34476307; PMCID: PMC8389879.

Introduction: Pediatric quality improvement (QI) collaboratives are multisite clinical networks that support cooperative learning. Our goal is to identify the contextual facilitators and barriers to implementing QI resuscitation interventions within a multicenter resuscitation collaborative. 

Raymond TT, Pandit SV, Griffis H, Zhang X, Hanna R, Niles DE, Silver A, Lasa JJ, Haskell SE, Atkins DL, Nadkarni VM; Pediatric Resuscitation Quality Collaborative (pediRES‐Q) Investigators.

J Am Heart Assoc. 2021 Jun 15;10(12):e020353. doi: 10.1161/JAHA.120.020353. Epub 2021 Jun 5. PMID: 34096341; PMCID: PMC8477851.

Background: Amplitude spectral area (AMSA) predicts termination of fibrillation (TOF) with return of spontaneous circulation (ROSC) and survival in adults but has not been studied in pediatric cardiac arrest. We characterized AMSA during pediatric cardiac arrest and hypothesized that AMSA would be associated with TOF and ROSC.

Wolfe HA, Wenger J, Sutton R, Seshadri R, Niles DE, Nadkarni V, Duval-Arnould J, Sen AI, Cheng A.

Pediatr Qual Saf. 2020 Jul 8;5(4):e319. doi: 10.1097/pq9.0000000000000319. PMID: 32766493; PMCID: PMC7351457.

Introduction: Clinical event debriefing functions to identify optimal and suboptimal performance to improve future performance. “Cold” debriefing (CD), or debriefing performed > 1 day after an event, was reported to improve patient survival in a single institution. We sought to describe the frequency and content of CD across multiple pediatric centers.

Esangbedo I, Yu P, Raymond T, Niles DE, Hanna R, Zhang X, Wolfe H, Griffis H, Nadkarni V; Pediatric Resuscitation Quality (pediRES-Q) Collaborative Investigators.

Resuscitation. 2020 Jan 1;146:56-63. doi: 10.1016/j.resuscitation.2019.10.039. Epub 2019 Nov 14. PMID: 31734222.

INTRODUCTION: Survival after in-hospital cardiac arrest (IHCA) has been reported to be worse for arrests at night or during weekends. This study aimed to determine whether measured cardiopulmonary resuscitation (CPR) quality metrics might explain this difference in outcomes.

Pfeiffer S, Lauridsen KG, Wenger J, Hunt EA, Haskell S, Atkins DL, Duval-Arnould JM, Knight LJ, Cheng A, Gilfoyle E, Su F, Balikai S, Skellett S, Hui MY, Niles DE, Roberts JS, Nadkarni VM, Tegtmeyer K, Dewan M; Pediatric Resuscitation Quality Collaborative Investigators.

Pediatr Emerg Care. 2021 Aug 1;37(8):e431-e435. doi: 10.1097/PEC.0000000000001748. PMID: 31045955; PMCID: PMC8809371.

Objectives: Code team structure and training for pediatric in-hospital cardiac arrest are variable. There are no data on the optimal structure of a resuscitation team. The objective of this study is to characterize the structure and training of pediatric code teams in sites participating in the Pediatric Resuscitation Quality Collaborative.

Sweberg T, Sen AI, Mullan PC, Cheng A, Knight L, Del Castillo J, Ikeyama T, Seshadri R, Hazinski MF, Raymond T, Niles DE, Nadkarni V, Wolfe H; pediatric resuscitation quality (pediRES-Q) collaborative investigators.

Resuscitation. 2018 Jul;128:181-187. doi: 10.1016/j.resuscitation.2018.05.015. Epub 2018 May 26. PMID: 29768181.

Background: The American Heart Association recommends debriefing after attempted resuscitation from inhospital cardiac arrest (IHCA) to improve resuscitation quality and outcomes. This is the first published study

detailing the utilization, process and content of hot debriefings after pediatric IHCA.

Niles DE, Duval-Arnould J, Skellett S, Knight L, Su F, Raymond TT, Sweberg T, Sen AI, Atkins DL, Friess SH, de Caen AR, Kurosawa H, Sutton RM, Wolfe H, Berg RA, Silver A, Hunt EA, Nadkarni VM; pediatric Resuscitation Quality (pediRES-Q) Collaborative Investigators. 

Pediatr Crit Care Med. 2018 May;19(5):421-432. doi: 10.1097/PCC.0000000000001520. PMID: 29533355.

Objectives: Pediatric in-hospital cardiac arrest cardiopulmonary resuscitation quality metrics have been reported in few children less than 8 years. Our objective was to characterize chest compression fraction, rate, depth, and compliance with 2015 American Heart Association guidelines across multiple pediatric hospitals.

Scientific Conference/Symposium Abstracts

In chronologic order


Landscape of In-Hospital CPR Quality Metrics Across an International Pediatric Resuscitation Collaborative. Dana E. Niles, Jordan Duval-Arnould, Sophie Skellett, Lynda Knight, Felice Su, Tia Raymond, Todd Sweberg, Anita I. Sen, Dianne L. Atkins, Stu Friess, Jimena del Castillo, Allan DeCaen, Hiroshi Kurosawa, Annemarie Silver, Robert Sutton, Heather Wolfe, Robert Berg, Vinay Nadkarni. (ReSS2017)

Characterization of CPR Performance Metrics Early Versus Late in Pediatric In-hospital Resuscitations.  Elena Insley, Elaine Gilfoyle, Todd Sweberg, Jordan Duval-Arnould, Dana E. Niles, Ivie Esangbedo, Tia Raymond, Ichiro Watanabe, Annemarie Silver, Vinay Nadkarni (ReSS2017)

Characteristics of Chest Compressions Immediately Before and After Interruptions during Pediatric In-hospital CPR.  Jordan Duval-Arnould, Dana E. Niles, Ryan W. Morgan, Tia Raymond, Priscilla Yu, Dianne Atkins, Stu Friess, Elaine Gilfoyle, Denise Welsby, Matthew Braga, Annemarie Silver, Vinay Nadkarni. (ReSS2017)

Analysis of the process and content of hot debriefing after pediatric in-hospital cardiac arrest in a multicenter quality collaborative.  Todd Sweberg, Anita I. Sen, Adam Cheng, Lynda Knight, Jimena del Castillo, Takanari Ikeyama, Tia Raymond, Dana Niles, Vinay Nadkarni, Paul Mullan, Heather Wolfe. (ReSS2017)

Variability in Pediatric Cardiac Arrest Management Across Sites in a Multicenter Pediatric Resuscitation Collaborative.  Sholeen Nett, Anita I Sen, Dianne Atkins, Adam Cheng, Jordan Duval-Arnould, Ivie Esangbedo, Stuart Friess, Elaine Gilfoyle, Sarah E Haskell, Dori-Ann Martin, Vinay Nadkarni, Dana Niles, Priti Jani, Joan S Roberts, Javier Urbano, Ichiro Watanabe, Heather Wolfe, Priscilla Yu, Elizabeth A Hunt. (ReSS2017)


Association of 2015 AHA CPR quality metrics and 24Hour Survival Across 10 Pediatric Critical Care Sites.  Hunt, Raymond, Gulfoyle, Duval-Arnould, Niles, Sweberg, Wolfe, Jani, Martin, Tegtmeyer, Nett, Sen, Roberts, Friess, Su, Haskell, Silver, Nadkarni. (SCCM2018)

Characterization of a new CPR Performance Metric in Children: Chest Compression Release Velocity.  Jordan Duval-Arnould, Dana Niles, Elena Insley, Annemarie Silver, Heather Wolfe, Vinay Nadkarni. (SCCM2018)

CPR Coach Role Improves Depth, Rate and Return of Spontaneous Circulation.  Pfeiffer, Duval-Arnould, Wenger, Lauridsen, Hunt, Haskell, Atkins, Knight, Cheng, Gilfoyle, Su, Balikai, Skellett, Hayes, Mok, Niles, Nadkarni, Tegtmeyer, Dewan. (SCCM2018)

Does CPR quality improvement bundle implementation result in better quality CPR during In-Hospital Cardiac Arrest?  Nett, Sen, Cheng, Duval-Arnould, Esangbedo, Friess, Gilfoyle, Haskell, Martin, Nadkarni, Niles, Jani, Roberts, Urbano, Watanabe, Wolfe, Yu, Hunt. (SCCM2018)

Accuracy of Team Perception of Performance With Actual CPR Quality Metrics in Children.

Lynda Knight; Todd Sweberg; Paul Mullan; Anita Sen; Matthew Braga; Priti Jani; Felice Su; Shilpa Balikai; David Kessler; Joan Roberts; Aaron Donoghue; Jesse Wenger; Dana Niles; Vinay Nadkarni; Marc Berg for  the pediRES-Q Investigators. (ReSS2018)

Effect of Defibrillation Dose and Waveform Characteristics on Defibrillation Success in Pediatric In-hospital Cardiac Arrest.  Tia Tortoriello Raymond; Jordan Duval-Arnould; Weilun Quan, Sam Chai; Lyndsay Ryerson; Javier Lasa; Peter Meaney, Robert Berg, Vinay Nadkarni, Dana Niles; Annemarie Silver; Allan de Caen; Dianne Atkins for the pediRES-Q Investigators. (ReSS2018)

“Cold” Debriefing after Pediatric In-Hospital Cardiac Arrests.  Heather Wolfe, Jesse Wenger, Robert Sutton, Dana Niles, Vinay Nadkarni, Jordan Duval-Arnould, Anita Sen, Adam Cheng, for the pediRES-Q Investigators. (ReSS2018)

Characteristics of Chest Compressions in Pediatric Patients with and without Congenital Heart Disease During Pediatric In-hospital CPR Across an International Resuscitation Collaborative.  Tia Raymond, Jesse Wenger, Jordan Duval-Arnould, Annemarie Silver, Betsy Hunt, Dana E. Niles, Vinay Nadkarni. (PCICS2018)

Is CPR Quality Worse During Nights and Weekends in the Cardiac ICU?  P. Yu, I. Esangbedo, H. Griffis, R. Hanna, V. Nadkarni, D. Niles, T. Raymond for the Pediatric Resuscitation Quality (pediRES-Q) Investigators. (PCICS2018)


Is CPR Quality Worse at Night and on Weekends?  Ivie Esangbedo, Priscilla Yu, Tia Raymond, Dana Niles, Richard Hanna, Xuemei Zhang, Heather Griffis, Vinay Nadkarni; for the Pediatric Resuscitation Quality (pediRES-Q) Collaborative Investigators. (SCCM2019)

Post-Cardiac Arrest Care Guidelines and Survival to Hospital Discharge in a Pediatric Resuscitation Collaborative. Raymond, Buysse, Su, Wenger, Hunt, Duval-Arnould, Sen, Niles, Griffis Nadkarni, Topjian for the Pediatric Resuscitation Quality (pediRES-Q) Collaborative Investigators. (SCCM2019)

Outcomes After Extracorporeal Cardiopulmonary Resuscitation in Pediatric In-Hospital Cardiac Arrest: Do Quantitative CPR Metrics Matter?  Tia Raymond, Priscilla Yu, Ivie Esangbedo, Todd Sweberg, Javier Lasa, Dana Niles, Xuemei Zhang, Heather Griffis, Richard Hanna, Vinay Nadkarni. (ReSS2019)

Delivery of CPR in Patients with Single and Biventricular Cardiac Disease.  Todd Sweberg, Tia Raymond, Priscilla Yu, Ivie Esangbedo, Kelly Bora, Dana E. Niles, Heather Griffis, Xuemei Zhang, Richard Hanna, Vinay Nadkarni. (ReSS2019)

Post-Cardiac Arrest Care Guidelines and Survival to Discharge in a Pediatric International Resuscitation Collaborative.  Tia Raymond, Janie Garza, Corinne Buysse, Felice Su, Jesse Wenger, Elizabeth Hunt, Jordan Duval-Arnould, Anita Sen, Dana Niles, Heather Griffis, Vinay Nadkarni, Alexis Topjian. (Cardiology2019)


Association of Hyperoxia with Survival after Cardiac Arrest in Pediatric Resuscitation Collaborative.  Buysse C, de Jonge R, Scholefield B, Niles D, Nadkarni VM, Topjian AA. (SCCM2020)

Post-cardiac Arrest Care Compliance and Neuro Outcome in a Pediatric Resuscitation Collaborative.  Buysse C, de Jonge R, Hanna R, Raymond T Niles DE, Su F, Friess S, de Caen A, Nadkarni VM, Topjian AA. (SCCM2020)

Contextual Factors Affect Implementation of Pediatric CPR Quality Improvement Interventions. Dewan M, Parsons A, Tegtmeyer K, Wenger J, Niles DE, Raymond T, Skellett S, Roberts J, Wolfe HA. (SCCM2020)

Chest Compression Pauses during Pediatric E-CPR Cannulation.  Lauridsen KG, Lasa JJ, Raymond T, Yu P, Niles DE, Sutton RM, Morgan RW, Berg RA, Griffis H, Hanna R, Zhang X, Nadkarni VM. (SCCM2020)

Chest Compression Pause Duration is Associated with Worse Survival Outcomes following Pediatric In-hospital Cardiac Arrest. Lauridsen KG, Morgan RW, Berg RA, Niles DE, Kleinman M, Zhang X, Griffis, Del Castillo J, Skellett S, Lasa JJ, Raymond T, Duval-Arnould J, Sutton RM, Nadkarni VM. (ReSS2020)  

Cerebral Oximetry During Pediatric In-hospital Cardiac Arrest. Esangbedo ID, Rajapreyar P, Kirschen M, Hanna R, Niles DE, Zhang X, Griffis HM, Francoeur C, Wakeham MK, Petersen T, Topjian AA, Nadkarni VM, Raymond TT. (ReSS2020) 

Association of End Tidal Carbon Dioxide >20 mmhg with Pediatric In-hospital Cardiac Arrest Quality of CPR and Survival. Yu P, Sutton RM, Hanna R, Zhang X, Griffis HM, Niles DE, Berg RA, Christoff A, del Castillo J, Ikeyama T, Gilleland J, Abulebda K, Raymond TT, Nadkarni VM. (ReSS2020) 

Effect of Amplitude Spectral Area on Termination of Fibrillation and Outcomes in Pediatric Cardiac Arrest. Raymond TT, Pandit S, Griffis HM, Zhang X, Hanna R, Niles DE, Silver AE, Lasa JJ, Haskell SE, Atkins DL, Nadkarni VM (ReSS2020) 


Prevalence of Inappropriate Defibrillation Attempts During Pediatric In-Hospital Cardiac Arrest. Gray J, Raymond T, Atkins D, Tegtmeyer K, Niles D, Nadkarni V, Dewan M, for the pediRES-Q Investigators. (ReSS2021)

Characteristics and Outcomes in COVID-19 Pediatric In-hospital Cardiac Arrest. Patients. Lauridsen KG, Sweberg T, Haskell S, Gawronski O, Niles D,Dewan M, Skellett S, Duval-Arnould J, Bottari G, Nadkarni V, Sen AI for the pediRES-Q Investigators. (ReSS2021)

Post-Cardiac Arrest Care Implementation in PICUs Belonging to the pediRES-Q Collaborative.

Jessica A Barreto MD MS, Jesse Wenger MD, Maya Dewan MD, Alexis Topjian MD, Joan Roberts MD on behalf of the pediRES-Q Investigators. (ReSS2021)


Chest Compression Release Velocity In Pediatric In Hospital Cardiac Arrest: A Descriptive Study.

Jennifer E Hayes, Thomas Rappold, Jordan Duval-Arnould, Dana Niles, Robert M Sutton, Annemarie E Silver, Marc Berg, Kasper G Lauridsen,  Vinay M Nadkarni, for the pediRES-Q Investigators. (ReSS2022)

Cerebral Near-infrared Spectroscopy During Pediatric In-hospital Cardiac Arrest: A Multicenter, Observational Study.

Esangbedo I, Rajapreyar P, Kirschen M, Niles D, Je S, Topjian A, Nadkarni V, Raymond T for the Pediatric Resuscitation Quality (pediRES-Q) Collaborative Investigators. (ReSS2022)

Impact Of Hot Debriefing Programs On Pediatric Cardiopulmonary Resuscitation Quality A.nd Outcomes.

Priti Jani, Todd Sweberg, Maya Dewan, Ken Tegtmeyer, Paul Mullan, Heather Grifis, Xuemei Zhang, Dana Niles, Vinay M Nadkarni, Heather Wolfe, for the Pediatric Resuscitation Quality Collaborative (pediRES-Q) Investigators. (ReSS2022)


Association of Chest Compression Release Velocity with Survival Outcomes Following Pediatric Cardiac Arrest.

Rappold, Thomas; Hayes, Jennifer; Niles, Dana; Zhang, Xuemei; Griffis, Heather; Silver, Annemarie; Berg Marc; Lauridsen, Kasper; Sutton, Robert; Wolfe, Heather; Raymond, Tia; Nadkarni, Vinay; for the pediRES-Q Investigators. (SCCM2023)

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