The 2023 pediRES-Q Annual Report is Out!

#pediRES-Q

Abhay Ranganathan has a provided a 2023 pediRES-Q report, detailed below. We have had a greatyear, made impactful by everyone involved, and look forward to continuing this work and more in 2024. Hope you have a pleasant New Year’s ahead!

Pictured: Sango Je, Abhay Ranganathan, Kelly E. Papili, Cassie Simpson-Dukes, Vinay Nadkarni

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pediRES-Q has continued to grow both in size and scope over 2023. We welcomed new partners to the platform, encouraged new studies, published new standards for post arrest care, established a pipeline for supporting resource limited sites, and hosted our annual Nicoletti conference to facilitate discussions around cutting-edge resuscitation science and standard of care.

As much success as we have had, this year has not been without challenges: we continue to make steady progress with onboarding partner sites outside the United States, whilst navigating varying regulatory requirements. In our efforts to establish regional centers within the pediRES- Q network, we are creating project pipelines for sites to create local registries for post arrest care and quality improvement.

New partners that joined us in 2023:

University of Kentucky (Lexington, KY, United States of America)
Kaiser Permanente (Los Angeles, CA, United States of America)
Boston Children's Hospital (Boston, MA, United States of America)
Children's Hospital Colorado (Aurora, CO, United States of America)
North Carolina Children's Hospital (Chapel Hill, NC, United States of America)
Upstate Golisano (Syracuse, NY, Unites States of America)
Cedars-Sinai Medical Center (Los Angeles, CA, United States of America)
Children's Omaha (Omaha, NE, United States of America)
Nemours Children’s Hospital (Wilmington, DE, United States of America)
Children's Minnesota (Minneapolis, MN, United States of America)
Children's Hospital at Montefiore (Bronx, NY, United States of America)
Lurie Children's Hospital (Chicago, IL, United States of America)
Sabara Infantil Hospital (São Paolo, Brazil)
Medical University of South Carolina (Charleston, SC, United States of America)

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pediRES-Q Site Funding

Thanks to continued support from our sponsors, we were able to establish a funding mechanism for our partners to access supplemental funding to continue participation in pediRES-Q. For 2023, 2024, and 2025, pediRES-Q will distribute $25,000 amongst those site that apply for funding.

Awardees for the 2023 cycle are:

Tokyo Metropolitan Children's (Tokyo, Japan)
Alberta Children's (Calgary, Canada)
Stollery Children's (Edmonton, Canada)
Starship Children's Hospital (Auckland, New Zealand)
Great Ormond Street Hospital (London, England)
Children's Healthcare of Atlanta (Atlanta, United States of America)
Instituto Roosevelt (Bogotá, Colombia)

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pediRES-Q Data

Across the network in 2023, investigators helped grow the registry by 15% by entering over 400 new events. We are continuing to see a steady increase in ROSC, Survival to Hospital Discharge (SHD), and Favorable Neurological Outcomes (FNO) in 2023 compared to 2022.

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pediRES-Q Learning Laboratory

In 2023, we established a yearly rotating scheme for the Manuscript Oversight Committee (MOC) to simultaneously help provide feedback for manuscript requests and help young investigators build reviewer experience by getting a chance to be on the MOC and benefit from the experience of senior committee members.

Our MOC for 2023:

Robert Berg, CHOP
Maya Dewan, CCHMC
Javier Lasa, UTSW
Vinay Nadkarni, CHOP
Tia Raymond, Medical City

Over this year, pediRES-Q investigators published the following manuscripts:

Association of blood pressure with neurologic outcome at hospital discharge after pediatric cardiac arrest resuscitation
How do we detect and respond to clinical deterioration in hospitalized children? Results of the Pediatric Care BefOre Deterioration Events (CODE) survey
CPR quality and outcomes after extracorporeal life support for pediatric In-Hospital cardiac arrest
Inappropriate Shock Delivery Is Common During Pediatric In-Hospital Cardiac Arrest

pediRES-Q investigators also presented the following abstracts:

SCCM

Association of Chest Compression Release Velocity with Survival Outcomes Following Pediatric Cardiac Arrest

WCCPCS

Outcomes After Pediatric Extracorporeal Cardiopulmonary Resuscitation: Do Quantitative CPR Metrics Matter?
Delivery of CPR in Patients with Single and Biventricular Cardiac Disease: A Report from the Pediatric Resuscitation Quality Collaborative
Are Chest Compression Quality Metrics Different in Children With And Without Congenital Heart Disease: A Report From The Pediatric Resuscitation Quality Collaborative

ReSS

Optimization of pediatric CPR and the role of Interposed Abdominal Compression
Association of cumulative oxygen and carbon dioxide levels with favorable neurologic outcome at hospital discharge in pediatric cardiac arrest

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How we connected as a platform

Teleconferences

In 2023, we held eight pediRES-Q investigator teleconferences with an average attendance of 35 persons and discussed 14 topics in resuscitation science and best practices including projects like:

Interposed Abdominal Compression-CPR
Long term post CA follow up for outcomes
Socioeconomic impact on post CA outcomes

Beatrice Nicoletti CHOP Resuscitation Science Center and Pediatric Global Resuscitation Alliance Conference

We hosted 126 investigators from across 14 countries at our Nicoletti conference on November 9th and 10th 2023 and had several topics presented in the following areas of resuscitation science:

Intra-arrest management (Ventilation rates, ECPR)
Hot topics in pediatric resuscitation (CPR guidelines, bridging the gap between NRP and PALS, intra-arrest ECG: present and future state)
Translational and Clinical research (Mitochondrial-directed therapies, post arrest blood pressure biomarkers, cerebral auto regulation)

We also facilitated round table discussions to encourage care providers to discuss topics in the following areas: